Please join us for the last seminar before Christmas on ‘Developing tools to map the brain at synaptic resolution’ presented by Dr Marta Costa (Dept of Genetics) and Dr Philipp Schlegel (Dept of Zoology/LMB). This seminar is to be held at the Postdoc Centre on Mill Lane on 7th December, 6:30pm-8:00pm, with free pizza and beer/wine. All (students, PIs, technicians) are welcome.
‘The Drosophila mushroom body (MB) is a complex neuropil, used as a model for associative memory storage and state-dependent behaviours. In an international effort, the speakers are generating a wiring diagram of the MB and MB-associated neurons at synaptic resolution using an electron microscopy volume of the entire fruit fly brain.
One of the analytical tools developed for that purpose is NBLAST, a neuron similarity algorithm. NBLAST is able to distinguish neuron types and identify new ones, as well as organise large datasets of neurons into groups of similar ones, making it easier to deal with big volumes of data. The speakers will describe the MB project, touching on technical challenges, the NBLAST algorithm, and its available resources’.